• Cdc7
• References
• Monogram
• Slides

References

1.     Hughes, S., et al., 2012. Crystal structure of human CDC7 kinase in complex with its activator DBF4. Nature Structural & Molecular Biology 19: 1101-1107.

2.     Masai, H. and Arai, K., 2002. Cdc7 Kinase Complex: A Key Regulator in the Initiation of DNA Replication. Journal of Cellular Physiology 190: 287-297.

3.     Lei, M., et al., 1997. Mcm2 is a target of regulation by Cdcy-Dbf4 during the initiation of DNA synthesis. Genes and Development 11: 3365-3374.

4.     Protein identification and analysis tools on the ExPASy server. Gasteiger, E. et. al. In J. M. Walker (Ed.) The proteomics protocols handbook. Totowa, New Jersey: Humana Press Inc. 2005.

5.     Protein Data Bank. https://www.rcsb.org/structure/4F99. 

6.     Goldsmith, E., et al., 2007. Substrate and Docking Interactions in Ser/Thr Protein Kinases. Chemical Reviews 107: 5065-5081.

7.     Yu, L., et al., 2010. Role of Mg2+ ions in protein kinase phosphorylation: insights from molecular dynamics simulations of ATP-kinase complexes. Molecular Simulation 37: 1143-1150.

8.     Jackson, A., et al., 1993. Cell Cycle Regulation of the Yeast Cdc7 Protein Kinase by Association with the Dbf4 Protein. Molecular and Cellular Biology 13: 2899-2908.

9.     Oshiro, G., et al., 1999. Cell Cycle Control of Cdc7p Kinase Activity through Regulation of Dbf4p Stability. Molecular and Cellular Biology 19: 4888-4896.

10.  Labib, K., 2010. How do Cdc7 and cyclin-dependent kinases trigger the initiation of chromosome replication in eukaryotic cells? Genes & Development 24: 1208-1219.

11.  Basic Local Alignment Search Tool. National Center for Biotechnology Information. 2012. http://www.ncbi.nlm.nih.gov/blast/Blast.cgi.

12.  Dali server: conservation mapping in 3D. Nucl. Acids Res. 38, W545-549. Holm L, Rosenström, P. 2010.

13.  Protein Data Bank. https://www.rcsb.org/structure/6Q4G.